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Pittsburg, Kansas | The liver can create glucose. It is called gluconeogenesis. It creates what the body needs, as at least one cell in the body requires glucose, erythrocyte or something like that. All the other cells, including the brain can utilize ketones. In fact the brain prefers ketones over glucose and will pull ketones out of circulation if available. Glucose is a "push" feeding where ketones the brain "pulls" them out of circulation. This is from memory about a subject that I am NOT an expert. Just listened to a lot of presentations explaining it.
But the liver will only produce what the body needs in glucose. So if ketones are high and providing much of the energy needed, the liver simply may not be called to produce much glucose.
Think of a dual fuel irrigation engine running on Diesel and fumigated with natural gas. The engine has to have Diesel (glucose) because it is required for it to keep running. It can run totally on Diesel (glucose). But open the natural gas (ketones) valve a little and the Diesel govenor backs off the Diesel fuel delivery now that another fuel is providing some of the power. Open the NG (ketones) valve now even more and it is supplying the bulk of the fuel and combustion energy. So the Diesel is only providing a small amount.
So when the body is in a fasted state, utilizing body fat for fuel, ketones are high so not much glucose is needed. So the liver does not provide much via gluconeogenesis. Only what is required. Remember, no food is coming in. So all energy is being provided by stored up energy, body fat. Some of that body fat is being turned into ketones (the preferred fuel) and the required amount, and ONLY the required amount, of glucose via gluconeogenesis (liver).
Therefore in my non medical high school educated opinion, his reading of 40 was all the body required because all the rest of his energy needs were being provided by ketones (and technically some other things like free fatty acids but that gets into more details).
Clear as mud?
John
Edit: all of the above is talking about being in a fasted state, not a fed state. In a Fed state, what you eat determines which fuel and what ratio is being used.
Edited by John Burns 2/9/2020 22:08
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Snake diet update
