It would depend on the vaccine and disease in question.

For most people, getting vaccinated against anthrax is of highly dubious value. For those in the military, especially those who are in a MOS where they're dealing with NBC weapons, it is no doubt mandatory. For a civilian... unless you're in the Great Basin and are digging up areas where they buried cattle during the last outbreak of anthrax (in the 1930's), you'll rarely run across naturally occurring anthrax.


Skipping a DPT vaccination, by contrast, isn't a brilliant idea. 

The reason why so many parents today can afford to play roulette with children's health is the already dramatic reduction in communicable diseases in the last 100 years. Polio has seen a 99% reduction in cases over the last 100 years. Smallpox, once a deadly killer, has been eradicated.

Most people are utterly ignorant of history, and that includes child and infant mortality rates only three generations ago.