From acs.org:

 Originally, to ensure that the hatch remained sealed, a crane aboard the aircraft carrier U.S.S. Hornet was scheduled to lift the entire Apollo 11 capsule out of the ocean with the astronauts still inside. The capsule would then be placed in a special tent on the ship and the astronauts, wearing quarantine garments and gas masks, would be escorted to a mobile quarantine trailer aboard ship.

Unfortunately, to the horror of the biologists on the ICBC, the Apollo 11 capsule hatch door was opened prematurely in the Pacific Ocean, contrary to established planetary protection protocols. Someone on the ship had determined that the crane was unsafe, and frogmen were sent to open the crew hatch while the capsule was still floating in the ocean. This was a very serious breach of the planetary protection protocol—which was not pointed out in the news.

When the hatch door was opened, any lunar dust or microbes from inside the spacecraft could have been carried out into the air and the ocean. If there were any pathogenic organisms living in lunar soil, they now had a very warm and wet breeding ground in which to grow (36).

Years later, astronaut Buzz Aldrin said in a television interview that the mobile quarantine trailer in which the Apollo 11 crew was isolated had one serious flaw: Ants appeared to be going into and out of the trailer (37). If there were any Moon bugs, they would have gotten out with the ants.

Time magazine also reported that Aldrin began to drink heavily while in quarantine, which began a cycle of severe depression and alcoholism that lasted for the next nine years.