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Ethanol update. Can Ethanol help us FIGHT the Corona Virus?
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JonSCKs
Posted 4/1/2020 23:50 (#8157631 - in reply to #8157626)
Subject: Old School medicine treating Covid 19 with plasma from post virus herd


In order to get on top of the Virus Dr Fauci today talked about the use of old school medicine practices of taking the plasma from patients who have recovered from Covid19 and using the anti body's to inject into susceptible candidates to arrest the spread of the Virus.  He concluded that it was "the right direction to go."

https://www.usatoday.com/story/news/health/2020/04/01/coronavirus-plasma-therapy-5-us-patients-covid-19-donors/5090946002/

It was only four days before that, March 24, that the U.S. Food and Drug Administration began allowing researchers to request emergency authorization to test whether the plasma will help.

Plasma is the almost clear liquid that remains after red and white blood cells and platelets are removed from blood. It contains antibodies that can fight disease.

“The Chinese paper came out days ago, but days are feeling like years to me right now,” Wajnberg said, referring to a paper published March 27 in the Journal of the American Medical Association that described a test of convalescent plasma on five critically ill patients in Shenzhen, China.

For Wajnberg and thousands of other doctors worldwide “nothing feels fast enough.”

Methodist Hospital in Houston began recruiting plasma donors on Friday and gave the first plasma transfusions to a COVID-19 patient the following day.

It’s a gamble of time, energy and money, said William Schaffner, a professor of preventive medicine and infectious disease at Vanderbilt University School of Medicine in Nashville, Tennessee.

Convalescent plasma therapy has a mixed history of success. It's also time-consuming, expensive and difficult to deploy on a large scale. Even so, he’s all in favor of it.

“Any port in a storm — and we’ve got one heck of a storm out there,” he said.

The project, dubbed the National COVID-19 Convalescent Plasma Project, already has posted a protocol for clinical trials on its website.

"The world is downloading it," said Arturo Casadevall, one of the project's organizers and chairman of molecular microbiology and immunology at Johns Hopkins Bloomberg School of Public Health.

The plasma is being collected from patients who have recovered from COVID-19. Each donates a pint of blood. The red and white blood cells are separated out and put back into the donor’s bloodstream while the blood plasma, rich with virus-fighting antibodies, is kept aside.

The donor and the patient must be from compatible blood types and the plasma is tested for multiple diseases including COVID-19, HIV and hepatitis to ensure it can’t transfer other diseases.

While convalescent plasma (from the blood of people “convalescing,” or recovered, from a disease) has been used successfully in outbreaks of other diseases such as polio, measles and mumps, it’s by no means a slam dunk.

“It’s been used for other viruses, some with efficacy and some without,” said Wajnberg.

The plasma showed promising results in the small Chinese study posted as a preprint on March 27. Another preprint, from March 16, about plasma treatment in 10 severely ill patients in Wuhan, China, found similar results.

The idea of giving desperately ill patients blood plasma from people who have recovered from the same illness is more than a century old and was first used to treat a German child suffering from diphtheria.

But using it to fight COVID-19 has gone from one paper published in the Journal of Clinical Investigation on March 13 suggesting the idea of a large trial to a broad program in fewer than three weeks.

 

It’s become an international effort, showing the ability of scientists to self-organize at a speed unimaginable even three months ago. As of Monday, more than 100 researchers and 40 large hospitals in 20 states are involved in the effort to bring survivor plasma to clinical trials, according to project leaders.

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