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Ivermectin over/mis-dose...
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CMN
Posted 6/15/2021 08:21 (#9059859 - in reply to #9059647)
Subject: RE: Ivermectin over/mis-dose...


West of Mpls MN about 50 miles on Hwy 12
What I find interesting, is the "study" that started the Ivomec prevention/cures covid-19 mantra, used a 100 times safe for human use labeled dose.

And, in other more recent controlled studies, we are finding out it takes a much larger dose of Ivomec than what is currently approved for human use for the drug to be effective in treating covid-19.

https://www.news-medical.net/news/20200427/Ivermectin-alone-not-usef...

The approved dose of ivermectin alone not useful in treating COVID-19

https://www.covid19treatmentguidelines.nih.gov/therapies/antiviral-t...

Ivermectin is not approved by the FDA for the treatment of any viral infection.

Ivermectin has been shown to inhibit the replication of SARS-CoV-2 in cell cultures.13 However, pharmacokinetic and pharmacodynamic studies suggest that achieving the plasma concentrations necessary for the antiviral efficacy detected in vitro would require administration of doses up to 100-fold higher than those approved for use in humans.14,15 Even though ivermectin appears to accumulate in the lung tissue, predicted systemic plasma and lung tissue concentrations are much lower than 2 µM, the half-maximal inhibitory concentration (IC50) against SARS-CoV-2 in vitro.16-19 Subcutaneous administration of ivermectin 400 µg/kg had no effect on SARS-CoV-2 viral loads in hamsters. However, there was a reduction in olfactory deficit (measured using a food-finding test) and a reduction in the interleukin (IL)-6:IL-10 ratio in lung tissues.20


I find the not approved by the FDA for the treatment of any viral infection statement interesting too...I thought that is the reason many people are rejecting the approved for emergency use by the FDA covid-19 vaccines?
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