Yes I do it quite often as I have a stand alone photo printer that reads cards. It's  easy to load pictures from the computer onto the card. I also used to use it transfer files between computers before I had a flash drive as I had a USB card reader for my Xd camera cards.

 You will probably want to make sure though that you don't disrupt any files on the card that the camera or other device  has set up on the card though.