If you are catching the ones that are early and in the lower navel that is best. If they get to where you can drain you are behind big time. At that point the infection moves on up in the body and even though you might think you get them over it, you cant find them dead a couple months later. I had one do this and opened him up and you could see the discoloration on up into the body. I have found the best thing to do to the early ones is catch and pull the remainder of the navel cord off and if it will not pull off grab the navel and with a knife get the piece of necrotic tissue out of the end of the navel. If you let this stay in there it just keeps feeding infectiion on up. I then give Nuflor and if they are bad may need another dose in 3 days. Calves that hide out at birth are more prone to infection, the navel stays wet and does not dry off. You will see a cow licking the navel often and swelling. This getting the necrotic tissue at the navel is number one for me. If you dont do this the Nuflor does not seem to work sometimes.