Tipton, KS | John Burns - 6/26/2026 17:14
In other words, in humans...
People's opinions are not valid unless they reflect research findings.
The ketogenic diet was developed in the 1920s as a treatment for epilepsy, and thru the years, has been used for neurodegenerative diseases/disturbances---"cognitive decline, dementia, Parkinson's disease (PD), Alzheimer's disease (AD), Huntington's disease (HD), amyotrophic lateral sclerosis (ALS) and other neurodegenerative disorders."
But, I'm not aware of any longitudinal studies with different ketogenic approaches for 'healthy' subjects. Longest I've seen is 3 months. And Molly Gallop, PhD reflects my evaluation:
“We’ve seen short-term studies and those just looking at weight, but not really any studies looking at what happens over the longer term or with other facets of metabolic health,” said Molly Gallop, PhD
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Tidbits:
Tissues that are glucose dependent—"the red blood cells, some cells in the retina of the eye, some cells in the brain, and some in the kidney."
Liver --- has the capacity to make as much as 200 grams of glucose per day
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More Tidbits:
"In the 1960s, it was proposed that this state of low glucose and insulin, associated with the consumption of a KD [Ketogenic diets], could treat obesity and related metabolic health conditions by favoring fat usage over fat storage (7). "
"A recent study found that a KD increases cellular markers of aging in mice (10), and in 2019, Journal of the American Medical Association (JAMA) released a publication titled “The Ketogenic Diet for Obesity and Diabetes—Enthusiasm Outpaces Evidence” (11)."
https://www.science.org/doi/10.1126/sciadv.adx2752
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Mediterranean diet
