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Phainein7
Posted 6/25/2026 19:24 (#11684672 - in reply to #11684663)
Subject: RE: Glucose vs ketones


Tipton, KS
John Burns - 6/25/2026 19:05

The brain is undetermined.


"Even when the brain is heavily adapted to burning ketones, it still requires a baseline amount of glucose to synthesize specific neurotransmitters and keep certain cellular processes running. "
https://pmc.ncbi.nlm.nih.gov/articles/PMC3900881/
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"Ketones are highly efficient and can supply up to 60% of the brain's total energy requirements during periods of starvation"
https://pmc.ncbi.nlm.nih.gov/articles/PMC7699472/
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RE: "it still requires a baseline amount of glucose to synthesize specific neurotransmitters and keep certain cellular processes running"

Gluconeogenesis is quite relevant....the mammalian brain needs glucose....and there are some 4 different pathways glucose can be produced
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