Tipton, KS | John Burns - 6/25/2026 11:53
What that fails to say is that ketones are preferred fuel for both the brain and the heart.
What this vid indicates is there are some 4 different means to make glucose
Metabolism | Gluconeogenesis
https://www.youtube.com/watch?v=YpV96faQOZc
RE: "ketones are preferred fuel"
Speculation......"No multi-decade, true longitudinal human studies tracking a strict ketogenic diet directly to natural lifespan currently exist. True longevity research requires tracking human cohorts across entire lifespans, which is exceptionally difficult for restrictive, highly specific diets like keto."
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General Low-Carb Long-Term Trials (ARIC)
When expanding search criteria to generic low-carbohydrate longitudinal cohorts, data becomes highly mixed and highly dependent on food quality.
Animal vs. Plant Base: As highlighted in long-term data published via the National Institutes of Health (NIH), low-carb diets rich in plant-based fats and proteins correlate with lower all-cause and cardiovascular mortality. Conversely, low-carb diets heavy in low-quality animal fats often align with elevated risks.
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The U-Shaped Curve: Large longitudinal datasets like the Atherosclerosis Risk in Communities (ARIC) study showed a U-shaped mortality curve. Both extremely high-carbohydrate and generic low-carbohydrate approaches were associated with increased mortality compared to moderate consumption. However, these "low-carb" subjects were rarely in actual, clinical ketosis
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Observe the "may" word: "Very low-calorie ketogenic diet may scale back aging by 6 years"
https://www.medicalnewstoday.com/articles/could-a-low-calorie-keto-d...
We know there are people who lived past 100 years of age, who were not on a "low-calorie ketogenic diet"
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Mediterranean diet
