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NW Illinois | You didn't indicate if you self apply or have custom done. That makes a difference if you have access to respray policies. So I'll comment as if you self apply. I'm Quad Cities area with glyphosate resistant Giant Ragweed and mostly no tilled soybeans I custom spray where we don't use branded respray policies.
Pre in April is all about Waterhemp management and winter annual burndown. Zidua is best, but versions of Dual, Harness with Metribuzin, Authority, Valor are great cheap additions. For burndown, 24D alone is OK, but will be weak on chickweed. Roundup is OK but alone will miss marestail here. For us, nothing April applied will hold back giant ragweed.
Second pass is Memorial Day to 1st week of June, roughly V2-V3. This is giant ragweed management and waterhemp management zone. Enlist for all it's faults works excellent on giant ragweed, we can't use roundup effectively because of the resistance. Liberty alone struggles because here by Memorial Day, ragweed is already 8-12 inches tall in a basically spotless field and we just can't cover all the nodes or get good coverage on the small ones hidden under the big ones. Liberty at 32oz of old formulation with 3# of AMS is roughly $6.00 an acre, so would be hard to leave it out. Here is where the second layer of residual is important for waterhemp. If you don't control waterhemp here it makes 3rd pass cleanups very expensive without respray dollars.
Key I have found on 3rd pass application with straight Liberty is to spray it 3rd week of June or so. Fields look basically spotless and seems a waste, but by July 1 if not sprayed things are poking above the bean rows. At that point it's a Liberty/Enlist combo again and that's kills it being economical.
Edited by SimpleJoe 12/16/2025 07:31
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3 pass program in beans
