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| It is difficult to explain the validity of a meta analysis study when the summary is the only part that can be accessed through your links.
One can assume it is a valid study. It does raise issues that can inspire new studies to evaluate using new criteria in their studies. But these meta analysis studies are looking at 10-15 year old trials.
It can be an excellent guide for making parameters for new trials.
For a more recent analysis of more current and extensive trials the results made new recommendations to expand the parameters. New recommendations for statins expand their recommended use
https://www.nice.org.uk/news/article/statins-could-be-a-choice-for-m...
https://www.aafp.org/pubs/afp/issues/2023/0200/uspstf-statin-use-car...
In reference to the original poster, I was under the assumption that the friend had high cholesterol, which has a direct correlation to CVD. If the blood work showed up in a normal range, it would be highly unlikely that anything would be prescribed
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Hey John b ,others,question on statins
