Someone in Israel, I think it was, synthesized an mRNA COvID vaccine in March of 2020, as I recall, but it’s been a while.  So, 3 years 6 or 7 months?  Took a long weekend since the vaccine tech is more advanced than the older vaccine technologies is what I remember reading.

Posters here on NAT were alleging they had COvID as far back as Nov or Dec 2019, iirc.