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New cancer treatment
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OntarioCanuck
Posted 7/13/2014 20:38 (#3966646)
Subject: New cancer treatment


North of London

Apparently successful on dogs and since the genetic makeup is so similar to humans they think it can be adapted to treat humans too.

Amazing what technology can do these days.
https://ca.news.yahoo.com/blogs/geekquinox/new-immunotherapy-procedure-that-kills-cancer-in-dogs-could-help-save-human-lives--too-200318768.html?utm_medium=twitter&utm_source=twitterfeed
An Austrian research study basically took antibodies derived from mice and modified them so that they would readily bind with the receptors that coat dog cancer cells and actually inhibit tumor growth. The antibodies act like a key and the receptor antigens on the cell surface are the lock, so when the key is matched to that lock, it automatically triggers a self-destruct signal inside the diseased cell, setting off a chain reaction that begins to shrink the tumor. Even the body's own immune system gets in on the action and is able to more efficiently eradicate the cancer.

What clued the researchers in that they were on the right path was that those lock-like antigens coating dog tumor cells turned out to be a nearly identical match of those found on human cancer cells. Antibodies from mice, originally produced for humans, are then optimized to canines instead so that they zero-in and bind specifically to their cells.

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