Posted 5/20/2021 10:13 (#9014936 - in reply to #9014880) Subject: how much is too much?
Here are a couple more references for people to digest.
This one is from Mayo Clinic: https://www.mayoclinicproceedings.org/article/S0025-6196(15)00244-X/pdf From the article: Vitamin D intoxication associated with hypercalcemia, hyperphosphatemia, and suppressed parathyroid hormone level is typically seen in patients who are receiving massive doses of vitamin D in the range of 50,000 to 1 million IU/d for several months to years. Ekwaru et al16 recently reported on more than 17,000 healthy adult volunteers participating in a preventative health program and taking varying doses of vitamin D up to 20,000 IU/d. These patients did not demonstrate any toxicity, and the blood level of 25(OH)D in those taking even 20,000 IU/d was less than 100 ng/mL. For point of reference, a 25(OH)D level of 100 ng/mL is considered by the Institute of Medicine, the Endocrine Society, and many reference laboratories to be the upper limit of normal.1 There remains concern, however, that increasing vitamin D intake even by 400 IU/d increases the risk for kidney stones, especially in patients with a history of kidney stones.10 Despite this concern, there is no credible scientific literature suggesting that such vitamin D intake increases the risk for kidney stones.12,15 Similarly, data are weak regarding the association between vitamin D intake and cardiovascular calcifications.12 To the contrary, current evidence suggests that improvement in vitamin D status reduces the risk for hypertension, stroke, and myocardial infarction