The .270 is a flat-shooting cartridge that has been used to hunt everything from whitetails to bears. Big bears. I wouldn't advise shooting really big game with a .270 unless you're a really good shot, but it has been done. The gun writer Jack O'Connor was a huge .270 fan and used the .270 everywhere from Alaska to Africa.

My only beef against the .270 is limited bullet selection. You won't find many bullets outside the 130 grain to 150 grain range, and you won't find many bullets for match shooting. Almost all bullets made for the .270 are hunting bullets. If you're going to use the rifle for shooting at critters most all the time, and you don't want to fuss around with a large variety of bullets/loads, then this isn't an issue. There's absolutely nothing wrong with the .270 for hunting in the lower 48 states of the US. Ammo is widely available for it -- unlike some of the latest super-duper whizzy magnums, you can find .270 ammo in just about every gun shop, hardware store and bait shop around. You can find .270 ammo ranging in price from about $70 for 100 rounds in bulk to $40 for 20 rounds with ultra-premium hunting bullets.