There has been very good advice given: Lets recap ~

Change all fuel filters before leaving~

Fuel with good quality diesel fuel - Store bought Karoseen will work as well as #1 for a mix if you are really concerned. A 2½ gal jug in 25 gal tank will give you a 10% blend which is good to at least 0°F. That'll get you to N Iowa or Mn. Most big box hardware stores have jugs of Karoseen.

Mix anti-gel fuel treatment at the RECOMMENDED rates - this was debated last yr a bit - call the companies if you want, but they (howes and powerservice) both said too much can reverse the good their products offer. Both indicated that no more then a double douse at the most, but suggested following the recommended rates would give the same results.

Use your D-Max winter cover on the front of your grill. I do not know for sure, but have heard they come as standard equipment on all trucks shipped all across the US. If not, as suggested cover the front of the grill. Use cardboard or a old rug or even canvas. The idea is to break the wind from getting into your engine compartment so the cold doesn't overtake the heating of the engine compartment. The engine makes heat that keeps your fuel filter and fuel lines warm. With the grill covered, the engine will get enough air from other places to keep it cool - even pulling heavy loads. The factory grill and bumper covers do not have opening to allow air in and I've pulled in excess of 10000 lbs and had no over heating issues of engine or tranny. Do keep an eye on your temp gauge and trany temp gauge though.

As suggested, bring warm clothes - the predicted wind chills can be a killer - literly , if your flesh isn't protected. Chain binders and chains will stick to bare skin and instantlly frost bit it. It's not fun trying to pull your skin off metal .. . . it hurts.

Common experence / sence for northerners - seems it takes a few experences for the sence to sink in and not have fuel problems - and most of the fuel problems start with fuel filters.

Good luck and safe passage.